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81.
Chen ZY Jing D Bath KG Ieraci A Khan T Siao CJ Herrera DG Toth M Yang C McEwen BS Hempstead BL Lee FS 《Science (New York, N.Y.)》2006,314(5796):140-143
A common single-nucleotide polymorphism in the brain-derived neurotrophic factor (BDNF) gene, a methionine (Met) substitution for valine (Val) at codon 66 (Val66Met), is associated with alterations in brain anatomy and memory, but its relevance to clinical disorders is unclear. We generated a variant BDNF mouse (BDNF(Met/Met)) that reproduces the phenotypic hallmarks in humans with the variant allele. BDNF(Met) was expressed in brain at normal levels, but its secretion from neurons was defective. When placed in stressful settings, BDNF(Met/Met) mice exhibited increased anxiety-related behaviors that were not normalized by the antidepressant, fluoxetine. A variant BDNF may thus play a key role in genetic predispositions to anxiety and depressive disorders. 相似文献
82.
83.
Francis W. Beecher Esten Mason Suchismita Mondal Joseph Awika Dirk Hays Amir Ibrahim 《Euphytica》2012,188(3):361-368
The goal of this study was to identify quantitative trait loci (QTLs) associated with the maintenance of wheat grain quality following post-anthesis heat stress in a recombinant inbred line (RIL) population. The response to heat stress was measured using the sodium dodecyl sulfate sedimentation test (SDSS), a significant predictor of bread baking quality. SDSS scores were used to identify QTLs associated with grain quality and QTLs associated with quality stability were identified based on percent change in SDSS score between the heat stress and control treatments. Four QTLs were identified, located one each on linkage groups 1B, 1D, 4A, and 7A. The 1B, 1D, and 4A QTLs were associated with grain quality; the QTL on linkage group 7A was associated with quality stability. To confirm the detected QTLs, eighty advanced lines grown at three Texas nurseries were tested for relationships between allelic polymorphism at QTL linked markers and quality traits. Quality trait stability in the advanced lines was estimated using the coefficient of variability (CV%) of quality traits between nurseries. The analysis supported the relationship of the predicted QTLs on linkage groups 1B, 1D, and 4A with quality traits. The confirmed QTLs may be used in marker assisted selection (MAS) to develop wheat lines possessing superior quality traits. In addition, identification of genetic regions associated with this trait will aid the identification of the underlying genes. 相似文献
84.
Getachew AM Innocent G Trawford AF Reid SW Love S 《Tropical animal health and production》2012,44(4):757-762
A retrospective study was conducted to investigate the cause of rectal prolapse in working donkeys in Ethiopia. Analysis of
data on rectal prolapse cases obtained from the Donkey Health and Welfare Project clinic at the School of Veterinary Medicine,
Addis Ababa University, from 1995 to 2004 revealed that 83.6% (n = 177) of the cases were associated with Gasterophilus nasalis. The rest 10.7% and 5.7% were associated with work-related (overloading) cause and diarrhoea, respectively. The mean and
median numbers of G. nasalis recovered from the rectum of infected donkeys were 66 and 64, respectively, with a range of 2–195. Over 100 G. nasalis larvae were recovered from the rectum of 22% of the donkeys. Circular demarcated ulcer-like and deep circumferential pits
or ring-like mucosal lesions were found at the larval attachment sites. G. nasalis infection and the associated rectal prolapse were observed year round. However, the intensity of rectal larval infection
and incidence of rectal prolapse were significantly higher during the rainy season (P < 0.01). Age and sex of the donkeys had no significant effect on the intensity of rectal larval infection and incidence of
rectal prolapse (P > 0.05). 相似文献
85.
Frederick Cubbage Gustavo Balmelli Adriana Bussoni Elke Noellemeyer Anibal N. Pachas Hugo Fassola Luis Colcombet Belén Rossner Gregory Frey Francis Dube Marcio Lopes de Silva Hayley Stevenson James Hamilton William Hubbard 《Agroforestry Systems》2012,86(3):303-314
Silvopasture systems combine trees, forage, and livestock in a variety of different species and management regimes, depending on the biophysical, economic, cultural, and market factors in a region. We describe and compare actual farm practices and current research trials of silvopastoral systems in eight regions within seven countries of the world: Misiones and Corrientes provinces, Argentina; La Pampa province, Argentina; northwestern Minas Gerais, Brazil; the Aysén region of Patagonia, Chile; the North Island of New Zealand; the Southeast United States; Paraguay; and Uruguay. Some countries use native trees and existing forests; some use plantations, particularly of exotic species. Natural forest silvopasture systems generally add livestock in extensive systems, to capture the benefits of shade, forage, and income diversification without much added inputs. Plantation forest systems are more purposive and intensive, with more focus on joint production and profits, for small owners, large ranches, and timber companies. Trends suggest that more active management of both natural and planted silvopastoral systems will be required to enhance joint production of timber and livestock, achieve income diversification and reduce financial risk, make more profit, improve environmental benefits, and realize more resilience to adapt to climate change. 相似文献
86.
François Courbet Jean-Christophe Hervé Etienne K. Klein Francis Colin 《Annals of Forest Science》2012,69(2):125-138
• Introduction
Branch size and branch status (dead or alive) are important characteristics closely related to tree growth and wood quality. The aim of this study was to design models for the diameter and status of branches in Atlas cedar (Cedrus atlantica Manetti). 相似文献87.
88.
Context
Short rotation coppice (SRC) of hybrid Eucalyptus has been developed in France for almost 30 years for the production of pulp and paper and, since a few years, for energy purposes. In the traditional pulp production, only the stems are harvested, whereas the whole biomass may be harvested for energy purposes. Thus, a range of different harvest scenarios need to be considered with higher plantation densities or younger age of harvest for example.Aims
The objective of this study was to build models to estimate biomass and nutrient content of eucalyptus at different ages and so to estimate the production and the nutrient exportation of a SRC, depending on the different harvest scenarios.Methods
Over 250 trees were sampled in 16 stands at ages from 1 to 15 years. For each tree, biomass of different compartments and nutrient contents were recorded.Results
A complete set of equations for the four compartments (wood, bark, branches, and leaves) of aboveground biomass and for nutrient concentration was set up.Conclusion
Biomass and its allocation to different compartments and nutrient concentrations depended on the dimension and/or the age of the tree. In particular, nutrient concentration decreased with increasing tree diameter. 相似文献89.
Ron A. Miller Francis R. Pelsor Andrew S. Kane Renate Reimschuessel 《Journal of aquatic animal health》2013,25(2):121-128
Abstract The pharmacokinetic–pharmacodynamic predictor of antimicrobial activity for tetracyclines is reported to be the area under the concentration–time curve at steady state (AUCss) divided by the minimal inhibitory concentration of the targeted pathogen. Here, we estimate AUCss values for oxytetracycline (OTC) in serum of rainbow trout Oncorhynchus mykiss by using a destructive sampling study design. Seventy-two rainbow trout were fed OTC-medicated feed at 74.7 ± 1.5 mg/kg (mean ± SD) body weight (BW) by oral gavage for 10 consecutive days. Serum was collected from nine fish at 1, 3, 6, 8, 10, 12, 15, and 22 d after dosing began. Serum OTC concentrations were measured by high-performance liquid chromatography with a 0.01-μg/mL limit of detection. The average OTC AUCss was 29.2 μg × h/mL and was estimated using nonlinear mixed-effects modeling and bootstrap resampling techniques. The elimination half-life was estimated as 85.0 h, and the fraction of steady state achieved was estimated as 0.85. The calculated AUCss (24.8 μg × h/mL) following 10 d of oral dosing with 75 mg OTC/kg BW was less than the estimated AUCss. Results suggest that the pharmacokinetics of OTC exposure, including the AUCss, is better evaluated by using multiday dosimetry than by using a standard single-dose protocol. Received September 29, 2011; accepted January 30, 2012 相似文献
90.
Akash Tariq Kaiwen Pan Olusanya Abiodun Olatunji Corina Graciano Ningning Li Zilong Li Dagang Song Feng Sun Meta Francis Justine Dan Huang Shanxing Gong Bikram Pandey Muhammad Idrees Mohammed A. Dakhil 《植物养料与土壤学杂志》2019,182(4):586-596
Drought is one of the major environmental stresses altering forest productivity. However, nutrient availability can modulate drought resistance. Phoebe zhennan (gold Phoebe) is a high‐quality timber‐producing but threatened tree species in China, facing serious anthropogenic disturbances and abiotic constraints that restrict its growth and development. However, little attention has been given to designing adaptive strategies for its management by evaluating the possible role of major nutrients, particularly nitrogen (N), on its morphological and physio‐biochemical responses under water stress. To evaluate these responses, a complete randomized design was followed to investigate the effects of two irrigation levels (well‐watered and drought‐stressed conditions) and N fertilization treatments (with and without N). Drought stress significantly affected the growth of seedlings, as indicated by impaired photosynthesis, pigment degradation, disrupted N metabolism, over‐production of reactive oxygen species and enhanced lipid peroxidation. Nitrogen supplementation under drought stress had remarkable positive effects on the growth through physio‐biochemical adjustments as shown by higher level of nitrogenous compounds and up‐regulation of N‐associated metabolic enzymes activities which might be due to N‐mediated improved leaf relative water contents and photosynthetic efficiency. In addition, N application reduced oxidative stress and membrane damage, and maintained a high accumulation of osmolytes. However, in well‐watered seedlings N fertilization significantly improved root biomass and net CO2 assimilation rate suggesting high N‐use efficiency of the seedlings. These findings reveal that drought significantly affects the growth of P. zhennan, while N fertilization plays a crucial role in alleviating water stress damage by improving its drought tolerance potential at low metabolic costs. Therefore, N fertilization could be considered as an effective strategy for the conservation and management of P. zhennan in the face of future climate change. 相似文献